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Structure and dynamics of semaglutide- and taspoglutide-bound GLP-1R-Gs complexes
poorly soluble in organic solvents Stereochemistry: L-configuration (biologically active stereoisomer) The molecular structure features a quaternary ammonium group with three methyl substituents, a hydroxyl group, and a carboxylate function creating a zwitterionic compound at physiological pH
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5 Obesity is the main risk factor for obstructive sleep apnea, raising the possibility that weight loss may reduce incidence of this disorder, along with the need for continuous positive airway pressure (CPAP) devices
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