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L2-Cmu does not perturb glucose homeostasis in older mice We then evaluated effects of chronic IGF-1R mAb treatment on energy and glucose homeostasis in an initial cohort of older mice

Polymorphic variants of insulin-like growth factor I (IGF-I) receptor and phosphoinositide 3-kinase genes affect IGF-I plasma levels and human longevity: cues for an evolutionarily conserved mechanism of life span control

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The research demonstrated a specific molecular mechanism P9 binding to intercellular adhesion molecule 2 (ICAM-2) on intestinal L-cells triggering GLP-1 release

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