tirzepatide monograph (Mounjaro) Drug | PDF | Diabetes Drug of the Day: Tirzepatide

MACE-3, major cardiovascular event (cardiovascular death, nonfatal myocardial infarct, or nonfatal stroke)

In metabolic conditions such as diabetes, prolonged hyperglycemia can damage small nerve fibers through multiple pathways including oxidative stress, accumulation of advanced glycation end products, and microvascular insufficiency affecting nerve blood supply

The average change in weight with canagliflozin vs

The first primary outcome was cardiovascular death or worsening HF events, defined as the need for hospitalization, urgent intravenous drug therapy, or oral diuretic intensification with worsening HF

Small blood vessels (telangiectasia) may become visible on the surface of the skin, contributing to the overall redness