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4,6,7 Large observational analyses have reported lower risks for several neuropsychiatric outcomes, including substance use and psychotic disorders

Different mechanisms, different costs, different evidence bases

Comorbidities like type 2 diabetes and metabolic syndrome a cluster of metabolic disorders that includes obesity, dyslipidemia, hypertension, and insulin resistance, leading to chronic systemic inflammation

used proteomic approaches and identified HSP70 and HSP90 as potential targets mediating the protective effects of baicalin (Hou et al., 2022)

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