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The absence of liver toxicity with orforglipron, despite its primary route of elimination through hepatic CYP3A-mediated metabolism, suggests that the hepatotoxicity observed with danuglipron and lotiglipron was related to the specific chemical structures of those molecules rather than to the class of small-molecule GLP-1 agonists as a whole
doi: 10.1007/s00125-019-4963-5 16 GaribayDLouJ.LeeSAZaborskaKEWeissmanMHSlomaEet al
Understanding GLP-1 medication side effects is essential before considering them as part of your weight management journey
"Amino acid names and parlor games: from trivial names to a one-letter code, amino acid names have strained students' memories
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