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Lifestyle Factors Studies indicate that your diet and medication use can affect how long vitamin B12 stays in the body

Subcutaneous injection in the abdomen (at least two inches away from the navel), the front of the thigh, or the back of the upper arm

[17] Important safety considerations: Patients should call 999 or go to A&E immediately if they experience symptoms of severe allergic reaction such as difficulty breathing, significant swelling of the face or throat, or chest tightness

People taking heartburn medication, such as proton pump inhibitors, are at a higher risk for B12 deficiency and may benefit from alternative therapies to control/eliminate the heartburn or have regular Nutrient IV therapies and/or Vitamin B12 injections Elderly Vegans Vegetarians People with tapeworms Alcoholics Excessive use of antibiotics Excessive use of anti-convulsant medication Daily consumption of Aspirin may increase the risk for vitamin B12 deficiency

For example, sugar alcohols like sorbitol or mannitol (used in some chewable or effervescent preparations) can have osmotic effects, drawing water into the intestinal lumen and potentially leading to loose stools in sensitive individuals