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Consume glutathione-boosting foods such as onions, garlic, shallots, leeks, spinach, kale, collard greens, avocados, okra, parsley, peas, lentils, organ meats, broccoli, cabbage, and cauliflower
found that LPS stimulation led to an approximately 30-fold accumulation of succinate in mouse bone marrow-derived macrophages (BMDMs), which in turn specifically promoted the transcription and expression of IL-1 by inhibiting prolyl hydroxylase (PHD) and stabilizing HIF-1 ( During macrophage metabolic reprogramming, amino acid metabolism does not operate independently, but is embedded within the overall metabolic network
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Arteriosclerosis, Thrombosis, and Vascular Biology, 25 (4), 809814
Conclusions and perspective The GSH system is one of the most significant members of the cellular antioxidant defensive system, which is essential for eliminating excess ROS and protecting the myocardium in the presence of pathological cardiovascular factors
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