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PMID 34170647
So I have this saying: All medical diagnoses are false, but some are useful. And I take this from a saying in statistics, which is All models are false, but some are useful. And what that is is an appreciation that once you impose a model on the data, youre now biasing it towards the way you think about it
--- 4 Pharmacokinetics Parameter Detail Absorption Well absorbed orally Bioavailability ~100% Peak Plasma Time 34 hours Half-life ~70 hours (once daily dosing) Metabolism Liver (CYP2D6 & CYP3A4) Excretion Urine (major), feces Long half-life Once daily dosing
In vivo preclinical research involving rodent models assesses Dihexa's capacity to cross the blood-brain barrier following systemic administration
Discussing strategies for treatment continuityincluding addressing financial barriers, managing side effects proactively, and establishing realistic long-term goalsis essential for sustained benefit
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