Diabetes Dialogue: CATALYST Trial, Mifepristone, and Hypercortisolism in T2D, with John Buse, MD, PhD Diabetes Dialogue: CATALYST Trial, Mifepristone, and Hypercortisolism in T2D, with John Buse, MD, PhD This June 23, 2025 episode saw Isaacs and Bellini speak with John Buse, MD, PhD, of the University of North Carolina School of Medicine, about the phase 4 CATALYST trial
Insurance coverage, manufacturer discounts, and patient assistance programs significantly influence out-of-pocket costs, enabling broader access to therapy for insured populations
Semaglutide patients typically start the treatment with the lowest dose (0.25 mg) once weekly
In vivo, GPX4 deficiency in mice caused embryonic lethality, which may be correlated with increased ferroptotic cell death and enhanced LPO [119, 120]
Circ Res 97:10011008