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Figure 1 In addition to inhibiting pathways, membrane- and peptide-based strategies are being considered that would allow for the direct permeabilization or destabilization of biofilm cells
Abbreviations CKD: Chronic kidney disease TECs: Tubular epithelial cells UUO: Unilateral ureteral obstruction IRI: Including ischemia-reperfusion injury Fer-1: Ferrostatin-1 GPX4: Glutathione peroxidase 4 ACSL4: Acyl-CoA synthetase long-chain family 4 LPCAT3: Lysophosphatidylcholine acyltransferase 3 TFRC: Transferrin receptor protein 1 DMT1: Divalent metal transporter 1 FPN: Ferroportin CTGF: Connective tissue growth factor PDGFB: Platelet-derived growth factor subunit b FGF2: Fibroblast growth factor 2 4-HNE: 4-hydroxynonenal MDA: Malondialdehyde References Webster AC, Nagler EV, Morton RL, Masson P
However, they are exceptionally rich in vitamin C
2023;15(6):e45095
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