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A 2024 commentary in Lancet Diabetes & Endocrinology reported that GLP-1 users can lose anywhere from 25 to 39% of their muscle mass over a 9-to-18-month period, which is a rate of decline several times greater than normal age-related muscle loss
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Reduces Appetite: Targets the appetite control centers in the brain, effectively reducing hunger sensations
Clinical Evidence: The STEP Program The STEP clinical trial program is the most relevant evidence base for semaglutide's weight management indication
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