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4a) G6PD is commonly overexpressed in many myeloid and lymphoid malignancies leading to improved proliferation, but this effect can be abrogated by pharmacologic inhibition of G6PD 87
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Rapid progression also prevents accurate assessment of what concentration actually delivers results
We wondered whether, absent these enhancements, standard thiols might still react with H 2 O 2 at a meaningful rate, at least on a minute time scale at micromolar H 2 O 2
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