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There is also a 5-year Phase III clinical trial (NCT04822181) underway to investigate the efficacy and safety of semaglutide monotherapy in patients with NASH without cirrhosis, assessing the primary endpoints of progression of cirrhosis, regression of steatohepatitis, inflammation, and histological changes in balloon-like hepatocytes
10.1155/2015/130315 Oxid Med Cell Longev
It doesn't actually raise SPF on its own
The nausea at higher doses without adequate adaptation can be severe enough to force protocol abandonment entirely
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