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A 2012 study showed that whey protein produced a greater insulin response than white bread on a gram-for-gram basis [9]
The varying strategies of developing an ARKO line are important to note as characteristics such as the presence of the selection cassette, the promoter selected for transgene integration, the position of the loxP sites, or the utilized mouse background all likely contribute to differences in tissue selectivity, AR activity, and the resulting phenotypes [178, 201]
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16 The same principle has been used to demonstrate the clonal origin of the malignant transformation of acute leukemia 17 , 18 and chronic myelocytic leukemia, 19 and also the clonal nature of polycythemia vera, 20 primary thrombocythemia, 21 and paroxysmal nocturnal hemoglobinuria
