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Glutathione levels naturally decline with age, illness, and oxidative stress
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Furthermore, metformin has been shown to improve endometrial tolerance through its actions on the mitochondrial respiratory chain, activation of AMPK, suppression of NF-B, AGE production, and downregulation of inflammatory pathways (Jinno et al., 2021)
Lipid peroxidation induces ferroptosis through its destructive effects on cell membranes
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