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Well compare the claims made in the article to the data shown in the supplementary materials

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However, delivering GLP-1 receptor agonists through the skin presents substantial technical challenges

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Rebound hunger: As the appetite-suppression effects fade (usually noticeable 1-2 weeks after the last dose), many people experience "food noise" returning

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Preclinical models consistently support antidepressant-like effects mediated through serotonergic, anti-inflammatory, and neuroprotective pathways, providing strong mechanistic rationale

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