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Not only will dehydration worsen side effects, such as constipation, acute dehydration can significantly harm one's kidneys, especially if he or she is already experiencing the early stages of chronic kidney disease
PMID: 4349963 2
The overall effect contributes to their cardiovascular protective benefits
Given the peptide's short plasma half-life (~0.51 hour), daily dosing maintains more consistent exposure to the peptide's gene-expression-modulating effects
Its therefore important to continue eating a balanced diet with enough calcium, protein, and other nutrients even after weight loss
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