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2021 (Nature Communications) This study asked whether MOTS-c could restore physical performance in aged mice

This bypass also avoids first-pass metabolism, a process in which nutrients are partially broken down by the liver before they can be used

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(1) Studies on the Validation of In Vivo Obesity Intervention Effects A large number of in vivo animal experiments have confirmed that it exerts significant weightloss and fatreducing effects with favorable safety profiles.In a mouse model of highfat dietinduced obesity, administration of 20 mg/kg NNMTi daily for 11 days resulted in a significant reduction in body weight

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