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Any deviation from licensed dosing regimens should only occur under close medical supervision, as the risk-benefit profile at sub-therapeutic doses remains poorly characterised

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Journal of Alternative and Complementary Medicine

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People on anticoagulants such as warfarin, those with a recent history of severe or changing headaches, and individuals taking multiple central nervous system medications should consult their clinician before starting L-carnitine and may be advised to avoid it or undertake close monitoring.