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It is a chemical inhibitor of the enzyme nicotinamide N-methyltransferase (NNMT), which catalyzes the methylation of nicotinamide using S-adenosylmethionine as the methyl donor
Chemokine Profile of Synovial Fluid From Normal, Osteoarthritis and Rheumatoid Arthritis Patients: CCL25, CXCL10 and XCL1 Recruit Human Subchondral Mesenchymal Progenitor Cells
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References Vukojevic J, Milavi M, Perovi D, Ili S, ili AZ, uran N, trbe S, Zorii Z, Filipi I, Brei P, Seiverth S, Sikiri P
Clinicians can opt for an accelerated initiation with 160mg given at week 0, then 80mg at week 2, reducing to 40mg every fortnight thereafter[7678]
