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Cloning, functional analysis, and mitochondrial localization of Trypanosoma brucei monothiol glutaredoxin-1
We show that the secretion of glutathione, which eliminates harmful extracellular chemicals, is both necessary and sufficient for yeasts to collectively survive at high temperatures
Unlike synthetic compounds, glutathione is an endogenous molecule
Precision medicine approaches, guided by biomarkers such as GPX2, ATP7B, or H4K12la, may enable the stratification of patients for ferroptosis- or cuproptosis-inducing treatments
doi: 10.1111/j.1528-1167.2011.03033.x 152
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