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Do not use this article to diagnose a symptom, change a medication, or decide how to use an investigational compound

Wegovy received NICE approval in 2023 for weight management in adults with a BMI 35 kg/m (or 32.5 kg/m for people from South Asian, Chinese, other Asian, Middle Eastern, Black African, or African-Caribbean backgrounds) with at least one weight-related comorbidity

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However, gut microbial formation and catabolism of BB during oral l-carnitine metabolism in omnivores versus vegans/vegetarians, the human commensals that can utilize BB as a nutrient, and the relationship of this metabolite to the metaorganismal TMAO pathway and CVD had not yet been explored

(PubMed) da Costa KA, Niculescu MD, Craciunescu CN, Fischer LM, Zeisel SH