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Gut microbiome disruption Roaccutane can alter your balance of gut flora negatively while it is being taken
Drew Sinatra discusses how chronic NSAID use affects on the gut and provides alternatives you can take instead
doi:10.1016/j.soard.2018.12.002
Other examples of GLP-1 antagonists are liraglutide and tirzepatide (also a GIP agonist)
This circuit appears relevant to pleasure-based eating, binge eating, addiction, and other conditions involving reward-related behaviors
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