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Khoo M, Pressney I, Hargunani R, Tirabosco R
Authors Francis S
This study is especially novel in its approach, as it directly compares Akkermansia supplementation to a dietary intervention
Cons: lower per-capsule dose (175 mg) means you need 2-4 capsules daily, higher cost per effective dose than standard capsules, no Setria certification, sustained-release clinical data is less robust than liposomal data
The split dosing approach for tirzepatide follows comparable pharmacokinetic logic, though the drugs have different half-lives and receptor profiles
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