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Moreover, transferrin-conjugated nanoparticles have shown potential in the delivery of antileukemic drugs: Transferrin-conjugated lipid nanoparticles delivering an antisense oligonucleotide targeting BCL2 mRNA induced caspase-dependent apoptosis in AML cell lines and suppressed tumor growth of human AML xenograft tumors in mice (187, 188)

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doi: 10.1023/B:MCBI.0000044378.09409.b5 127 BehrmanHRKodamanPHPrestonSLGaoS

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