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This relationship is often overlooked in standard supplement discussions

Neurol Int

Oct 16 2018;61(4):R133-R160

Glutathione does not only neutralize free radicals: it also has the ability to reactivate other antioxidant molecules, such as vitamins C and E

The System Xc- enables the transfer of extracellular cystine to intracellular glutamate in a 1:1 proportion, which is succeeded by the production of GSH from intracellular cystine, aided by the actions of glutamate-cysteine ligase (GCL) and glutathione (GSS) [42, 44]