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Growth hormone deficiency is associated with longer lifespan, and high levels of growth hormone and IGF-1 are linked to shorter lifespan, as seen in species like dogs where larger breeds with higher IGF-1 levels have shorter lifespans than smaller breeds 10s

Overall compliance scores were high, ranging from 0.95 to 0.97 across Cagrilintide dose groups, and a post-hoc compiler average causal effect analysis yielded similar results, reinforcing that adherence strongly correlated with weight loss outcomes