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mAb #7F38), rabbit anti-insulin 1:500 (Cell Signaling Technology, #3014), mouse monoclonal anti-glucagon 1:2000 (Sigma-Aldrich, #G2654) and mouse anti-somatostatin 1:5000 (Invitrogen, #14-9751-80)

These data insisted of characteristics of subjects (especially the number or proportion of baseline metformin users), interventions, and the number of endpoints, hazard ratios (HRs) and confidence intervals (CI) for primary and secondary endpoints in both primary trial results and their subgroup results that reported cardiovascular outcomes with or without baseline metformin use

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