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First, unlike other DPP-4 inhibitors that are excreted largely in urine, linagliptin is mainly eliminated by a biliary route [131] and therefore does not require dose adjustment in patients with kidney disease [132, 133]

This myth is often fueled by anecdotal success stories that circulate online, leading people to believe that these medications are a one-size-fits-all solution

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[14] [15] The SELECT trial specifically showed that semaglutide 2.4 mg reduced the risk of cardiovascular death, non-fatal myocardial infarction, and non-fatal stroke by 20% compared to placebo in people with pre-existing cardiovascular disease and overweight or obesity