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The research team surveyed 27,885 users of the American genetic testing service '23andMe' who had experience taking GLP-1 drugs about their weight changes and side effects, and then searched the entire genome for related variants

Adjustments to the medication dosage or timing may be necessary, or other interventions might be recommended to manage sleep disturbances

Data from the Centers for Disease Control and Prevention (CDC) indicates that more than 42% of adults in the country are living with obesity, which is creating a large treatment-eligible population for incretin-based therapies

doi: 10.1186/s12885-025-13751-7 167