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Falck E, Karlsson S, Carlsson J, Helenius G, Karlsson M, Klinga-Levan K

The FDA identifies significant risks including lack of human safety data, potential for adverse immune reactions, and insufficient evidence regarding long-term effects, with the agency authorized to take enforcement action against compounding pharmacies that produce these substances for clinical applications

J Chromatogr A

Where it's most often discussed: Tissue repair and recovery models (especially tendons/ligaments and muscle) Wound healing and regenerative signaling Gut integrity and inflammation-related pathways Where it's not firmly established: Extensive, rigorous human studies designed to measure fat loss outcomes (fat mass, waist circumference, body fat percentage) That distinction matters