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In the component of primary outcome, persistent 50% eGFR decline from baseline was significantly reduced in semaglutide group (HR 0.73, 95% CI 0.590.89)
For weight management, research indicates that tirzepatide produces superior weight loss compared to semaglutide, with patients losing 20.2% of body weight versus 13.7%, respectively
[11] It appears to be safe in pregnancy
The Benefits of GLP-1 Agonists GLP-1 receptor agonists provide a wide range of health-enhancing effects beyond reducing body fat
While some studies have shown promising safety profiles, particularly in women with type 2 diabetes, additional confirmation is deemed necessary, especially for those without diabetes
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