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71 Therapeutic modulation of the autophagy-mitophagy axis in metabolic diseases Pharmacological interventions Several pharmacological agents already in clinical use exert metabolic benefits, at least in part, through activation of autophagy and mitophagy
For 28 days, animals were divided into four groups and treated daily with either LC (300 mg/kg), TMX (100 mg/kg), or both at the aforementioned doses
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Oxidative stress occurs when the body is overwhelmed by an excess of harmful molecules called free radicals, which it struggles to neutralise
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