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As the cells become weaker, they become more vulnerable to damage or apoptosis (cell death) from even small reductions in perfusion, which can occur if the individual becomes dehydrated or overheated, undergoes surgery, has a drop in blood pressure, engages is excess physical activity, has untreated sleep apnea, or experiences a traumatic shock
New York: Elsevier
Psychiatry 82, 472487
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Another example is the ubiquitin-editing enzyme A20 that impairs IL-6 secretion from adipocytes, leading to modulation of differentiation of MSCs [82]
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