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The introduction of GLP-1 agonists has marked a significant advancement in weight loss therapies

Further investigation is warranted to determine the optimal dosages and long-term effects of medications for T2DM and identify the variables contributing to heterogeneity through meta-regression analysis, mostly due to differences in study design, patient demographics, and treatment regimes

Oncotarget, 9(4), 54165423

However, this accessibility comes without the oversight, quality assurance, and clinical validation that characterizes approved weight loss medications

However, it is interesting that another study demonstrates that Prevotella were enriched at the genus level in OA patients (Han et al., 2025)