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When it comes to human trials, the data on DSIP is small, old, and mixed
Dr Pickart's own company sold topical formulations
Hepatology 50 (2), 434442 (2009)
In a March 31, 2026 warning letter, the agency said that products offered as Retatrutide or GLP-1-R peptide were unapproved new drugs under federal law
Some researchers have hypothesized that GLP-1 receptor stimulation might promote pancreatic duct cell proliferation or increase pancreatic enzyme secretion, but animal studies have not consistently demonstrated these effects at therapeutic doses
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