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Circadian rhythms and breast cancer: unraveling the biological clocks role in tumor microenvironment and ageing
This state has a dual effect on tumor cells, on one hand controlling several tumor-promoting features, on the other hand dynamically reprogramming immune cells and inducing tumor cells autophagy, apoptosis and ferroptosis (95)
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Off / washout (after the block): A typical research framing runs a defined block (commonly 812 weeks) followed by an off period before any subsequent block, rather than indefinite continuous use because long-term human data simply do not exist
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