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51 This evidence suggest that Danuglipron demonstrates potential for glycemic control and weight reduction in T2DM with an acceptable safety profile

Since nucleotide supply plays a critical role in DNA replication, we further performed DNA fiber assay by measuring the lengths of chase IdU-labeled DNA replication tracks that link to pulse CldU-labeling, which is a gold standard for assessing replication stress 32

This is often the key to fully resolving the condition, she adds