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The 25 to 30 day washout is the minimum for safe transition, and extending it slightly for those on higher tirzepatide doses is prudent risk management

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Mol Immunol (2019) 107:1020

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Theoretical considerations include: Potential interactions requiring monitoring: Other fat-loss agents or thermogenics (additive effects), growth hormone or growth hormone secretagogues (mechanism overlap), medications affecting glucose metabolism (monitor blood sugar despite AOD-9604s neutral glycemic effects)