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Autonomic Shift: Over time, the repeated heat stress encourages a shift toward parasympathetic dominance, supporting better stress resilience

Conditions such as metabolic stress, acute or chronic inflammation or nutritional availability all might impact the regulation of GLP-1 from intestinal or pancreatic sources [13]

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However, baseline liver function tests may be appropriate for patients with known liver disease or elevated transaminases, with individualized monitoring based on clinical judgment

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