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PubMed U.S
The Authors reported that treatment with incretins significantly suppressed the FSH-induced synthesis of progesterone through the inhibition of the expression of progestogenic factors and enzymes, whereas there was no significant effect on oestrogen synthesis by rat granulosa cells, thus suggesting the possible role of GLP-1 RA in the treatment of dysregulated steroidogenesis in PCOS [43]
These medications help override these adaptations while active, but their protective effect ends with discontinuation
10.1074/jbc.M307075200 J
The medicine turns on the GLP-1 receptors in your pancreas, which helps to make more of the hormone
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