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doi:10.1038/s41598-025-89293-6 44
A BMI of 27 or higher (overweight) qualifies if you also have one or more weight-related conditions, such as: Hypertension, which increases cardiovascular risk Type 2 diabetes, which has been closely linked to excess weight High cholesterol, which is known to raise the risk of heart disease Sleep apnea, often worsened by obesity Cardiovascular disease, such as a previous history of heart attack or stroke Step therapy rules Step therapy is a cost-control rule used by many insurers
They metabolize through different hepatic pathways
Hamed, A.H
Notably, a subset of activated HSCs is considered an important source of the pro-fibrotic and inflammatory effects of the SASP
