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Transwell migration assay 2 10 4 cells in serum-free medium containing 0.1% bovine serum albumin were placed into the upper chamber of the insert and 500 l complete medium were added into the bottom chamber

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We found that prolonged exendin-4-induced insulin secretion was increased in INS-1 832/3 and MIN6B1 cells after treatment with small interfering RNA (siRNA) to silence both -arrestins, and also in human EndoC-H1 40 beta cells lentivirally transduced with -arrestin-1 and -arrestin-2 small hairpin RNA (shRNA) (Fig

Establishing efficient, scalable chemical synthesis processes, optimizing reaction conditions and purification methods to ensure linker purity, yield, and batch consistency

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