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"Evaluation of high-protein supplementation in weight-stable HIV-positive subjects with a history of weight loss: a randomized, double-blind, multicenter trial." Am J Clin Nutr 88.5 (2008): 1313-21
ALCAR and ALA both have antioxidant properties that may enhance longevity
(Akkermansia muciniphila)
The key is having a clinician experienced with pediatric obesity guiding that decision, rather than extrapolating from adult guidelines
Setting realistic expectations is crucial: weight loss is gradual, with clinical trials showing approximately 15% weight reduction with semaglutide 2.4 mg at 68 weeks and up to 21% with tirzepatide at 72 weeks, though individual responses vary considerably
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