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Petek et al., 1999
The senescence response to wounding in aged organisms has not been fully characterized
Any compound that promotes new blood vessel formation carries a theoretical risk of supporting tumor vascularization in individuals with undetected malignancies
Gastrointestinal AE with cagrisema were more than with semagutide or cagrilintide monotherapy, however the SAE and AE leading to medication discontinuation were minimal and similar between the groups [87, 90] A programme of phase 3 clinical trials (REDEFINE) assessing the safety and efficacy of cagrisema in people with obesity (NCT05567796, NCT05394519, NCT05813925) is currently ongoing
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