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Nevertheless, the involvement of an hypomethylation cannot be ruled out, because in vitro studies suggest that a low concentration of homocysteine specifically inhibits endothelial cell regeneration and directly activates quiescent vascular smooth muscle cells through a mechanism involving decreased carboxymethylation of p21 ras (Lee and Wang, 1999

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10.1002/adfm.201908865 44 Luis Garcia-GimenezJ.MarkovicJ.DasiF.QuevalG.SchnaubeltD.FoyerC

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The original Ridley lens was placed in the posterior chamber, but the procedures technical difficulty and frequent complications led to modifications (12)

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