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It is about supporting the body in a way that improves how it functions over time

Historically, a physician could decide that he or she wanted to treat a patient with a certain drug and give it in a certain route of administration

In contrast, downregulated proteins were mainly associated with pathways involving platelet aggregation, chylomicron clearance, and defective coagulation factor IX activation, among others (Figure 5C)

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And in medicine, the general principle is that the lowest effective dose of any medication is preferable to the highest tolerated one