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Activation of these receptors results in some cells (such as epithelial cells or cells of the innate immune system) producing IL-32, a cytokine that activates/differentiates monocytes into macrophages and induces the production of proinflammatory cytokines such as IL-1, IL-6, and TNF by activating NF-B in differentiated macrophages [231,232,233]

Because this is a combination formula, increasing to two servings also doubles folate (to 1,000mcg) and vitamin D3 (to 2,000IU)

If plain water is difficult to tolerate because of nausea, sipping smaller amounts more frequently or adding slices of lemon, cucumber, or mint may make it easier to drink

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67% were women, and 33% were men