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In fact, an alternative hypothesis may consider the perceived negative effects of a very rapid weight loss in highly vulnerable subjects, including taste aversion, possibly disrupting rewarding circuit
Given the increasingly elucidated prominence of gut-related factors in osteoblasts/osteoclasts and bone formation/metabolism/maintenance, focusing on intestinal microecology and then targeting the distal bone tissue via the gutbone axis have been recognized as a feasible intervention strategy
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The combination of tretinoin and CoQ10 facilitate skin turnover and increases the protective antioxidant effects that improves skin integrity
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