El anlisis de los cambios durante el tratamiento con cada agente revel que los cambios en el peso fueron mayores para los que recibieron semaglutida en los puntos temporales de 3 meses (diferencia, 2,4%
Across the SURPASS trials documented in the Mounjaro FDA prescribing information, injection-site reactions occurred in approximately 3-7% of participants depending on dose, while true systemic allergic responses (hives spreading beyond the site, facial swelling, breathing difficulty) are rare
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However, some patients report musculoskeletal discomfort, which may relate to rapid weight loss, dehydration, or increased physical activity rather than direct medication effects
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